Projects

The individual members of the RU have a large international visibility and success in research project applications. The year 2017, during which the groundwork for this RU was laid, has seen the award of a large number of projects led by UR members.

European projects accepted:

• An H2020 FET-Open COPAC project: Coherent Optical Parallel Computing (2017-2020), coordinated by Françoise Remacle, Laboratory of Theoretical Chemistry
• An H2020 FET-Open MEMO project: Mechanics with Molecules (2017-2021), in which Anne-Sophie Duwez, NANOCHEM, participates as a PI
• An Interreg project involving the Mass Spectrometry Laboratory (PI De Pauw Edwin, Quinton Loic), EURLIPIDS, a Virtual Platform for Lipid Research     

• An infrastructure project: H2020 Infra EU_FT-ICR_MS - DLV-731077, in which the ultra-high resolution mass spectrometry platform is included in a European network for access to research infrastructure
• Monbaliu is Co-PI of a ERDF project (Intense4Chem) that aim at the development of intensified continuous-flow processes for the valorization of biomass to sustain a transition from the petrobased to the biobased chemical industry in Wallonia (2016-2022).

Projects  funded by the FNRS

Two EOS (Excellence Of Science, FNRS-FWO) projects have been granted in 2018:

• The laboratory of organic and biological analytical chemistry (PI JF Focant) participates in the project "Chemical Information Mining in a Complex World" DESMET coordination Gert, VUB
• The Mass Spectrometry Laboratory (PIs Edwin De Pauw and Loic Quinton) participates in the project "Ecological roles of cyclic lipopeptides from plant beneficial rhizobacteria: a chemical-biology approach to decipher primary functions of secondary metabolites", coordination HÖFTE Monica, UGhent

FNRS research projects and grants

• Prof. L Quinton received funding for the project "VenomsForLiege" - V4L (2020). This project aims at taking advantage of the potential of underexploited venoms to discover and characterize valuable modulators of SK and HCN ion channels. These receptors are targets of high interest for the understanding of the central nervous system functions.
• Prof. Anne-Sophie Duwez received funding for the project "Single-molecule force spectroscopy of molecular knots" (2020). This project aims to probe the intra-molecular interactions and mechanical properties of small molecule knots, by single-molecule force spectroscopy.
• Dr. J.-C. Monbaliu received funding for the project "Design of dynamic covalent exchanges in flow for the selective upgrading of biobased polyols" (2020).
• Dr. Gabriel Mazzucchelli, coordinator : 2018, MucoSWEATomics
• Dr. Nicolas Smargiasso, participant: 2018, "Aβ strains and oligomers in Alzheimer’s
• Dr. Françoise Remacle received funding for
  • « Ultrafast Photoinduced Bond Making, 2016-2019, PI Françoise Remacle”
  • « Attologic (2018-2019) », PI Françoise Remacle
• Prof. Anne-Sophie Duwez, coordinator, received funding for a Molecular Force Probe equipment (2018-2019).
• Dr. J.-C. Monbaliu received funding for
  •    « Reaction telescoping w/ unstable species » (2015-2016)
  • « µFluidic ligation toward peptides » (2017-2019)
• Prof. L. Delaude received funding for « Synthesis and Coordination of Zwitterionic Dithio­carboxylate Ligands Derived from Caffeine »

Projects fund by the region with the so called “poles”, that show the implication of the RU in the economic development of the region

Mecatech:

• a proprietary project has been granted by the pole Mecatech to the CART for special analytical developments
• CiTOS is involved in a project named “CARbon based MAtrix for PHARMaceutical purpose (CARMAPHARM)” (2015-2019)

Greewin: the CART is active in a project aiming at the design of new waste epuration systems for clinics. Its part consist in bringing the analytical support to industrial partners

Wallinov: MiliTher the present project aims to combine the use of microcarriers, decellularized liver matrix and different human primary liver cell types to produce highly functional, three-dimensional liver microspheroids. The MSlab has a crucial proteomics analysis contribution.

Biowin: (2016-2020):  Fast and Reliable ultra-sensitive Identification of Streptococcus B at delivery (FRISBY) (PI G  Eppe)

EUROSTARS (EU/RW): NxPAS – a novel non-invasive trace gas analyser platform targeting breath analysis (2015 – Investigator JF Focant).

Eurostar

The PIRMAH (Photoacoustic Infrared Microscope for Automated Histopathology) (E. DE Pauw) project aims at developing an ex-vivo infrared microscope prototype for automated histopathology. For the development and the validation of the performances of this microscope, FFPE (formalin-fixed paraffin embedded) and fresh-frozen tissues are used. The results obtained with this microscope are also compared with images obtained on other “well established” techniques such as mass spectrometry imaging (MSI). In this project, the mass spectrometry laboratory of the University of Liège is in charge of the MSI analysis of both FFPE and fresh-frozen tissues.

Fond de maturation RW: Breathprint – validation of potential asthma biomarkers for breath-based phenotyping (2017-2018 – Co-PI JF Focant)

Project funded by the « Department of Energy, Basic science office » , USA 

Dr. Fr. Remacle is a fully funded PI in the project “Exploiting Non-equilibrium Charge Dynamics in Polyatomic Molecules to Steer Chemical Reactions’”, Department of Energy, Basic science office  #DE-SC0012628 . Coordinator : Prof. Wen Li, Wayne State University, Detroit. 2018-2020

A new DoE project in the field of Quantum Technologies where F. Remacle is a fully funded Co-PI will be submitted for the end of May.